Stuck in the middle with you: why a broad-brush approach to defining central sensitisation does not help clinicians and patients

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17 March 2021

Stuck in the middle with you: why a broad-brush approach to defining central sensitisation does not help clinicians and patients

Central sensitization is increasingly interpreted as central nervous system hyperexcitability accounting for a general increase in sensitivity, and used to explain a variety of pain and non-pain symptoms. In this commentary, we argue that such a broad interpretation might not be clinically useful because it fails to distinguish one patient from another based on pathophysiological mechanisms and does not facilitate tailored treatment. We recommend that clinicians use a person-centred approach when assessing and managing patients, considering the different interacting processes/mechanisms that can contribute to a patient’s clinical presentation … ABSTRACT

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