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Fatigue in long COVID: An exploratory pragmatic randomized trial of osteopathic care plus physical therapy versus physical therapy alone

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25 April 2026

Fatigue in long COVID: An exploratory pragmatic randomized trial of osteopathic care plus physical therapy versus physical therapy alone

This study explored whether osteopathic care (OC) combined with physical therapy (PT) could be more effective than PT alone in reducing fatigue and functional limitations in adults with long COVID … MORE

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Patients With Chronic Low Back Pain Without Advanced Disk Degeneration Exhibit Gut Microbiome Dysbiosis: Evidence From an Age-­ , Sex-­ , and BMI-­ Matched Pilot Study

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19 April 2026

Patients With Chronic Low Back Pain Without Advanced Disk Degeneration Exhibit Gut Microbiome Dysbiosis: Evidence From an Age-­ , Sex-­ , and BMI-­ Matched Pilot Study

Chronic low back pain (LBP) is the leading cause of disability worldwide, yet its underlying pathophysiology remains poorly understood. Current diagnostic techniques rely heavily on imaging, which is insufficient for identifying inflammatory or systemic contributors. Emerging evidence suggests a role for gut microbiome dysbiosis in inflammatory pain pathways, yet its specific contribution to chronic LBP remains unclear. The aim of this study is to investigate gut microbiome alterations in chronic LBP patients compared to healthy controls … MORE

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Rethinking causation and mechanisms in osteopathy and physical intervention trial design: the positivist-realist continuum

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19 April 2026

Rethinking causation and mechanisms in osteopathy and physical intervention trial design: the positivist-realist continuum

There has been renewed interest in mechanistic theory within osteopathy and the associated musculoskeletal professions, particularly regarding the role mechanisms play in osteopathic, manual and other physical interventions. Evidence-Based Medicine which commits to evidential pluralism (explicit incorporation of mechanistic evidence to inform trial design, through the selection of more meaningful controls and measuring more relevant outcomes) is known as Evidence-Based Medicine Plus (EBM+).
This position paper introduces the concept of EBM+ to the osteopathy and MSK research community, and proposes the evolution of a theory of mechanisms that borrows from both positivist and realist traditions to better account for the mechanistic effects of physical interventions that are described in trials as specific, non-specific and contextual effects, and which have a relevance for clinical practice and education … ABSTRACT
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From touch to triage: translating the NAME model into clinical practice for enhanced neonatal assessment

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14 March 2026

From touch to triage: translating the NAME model into clinical practice for enhanced neonatal assessment

The Neonatal Assessment Manual scorE (NAME) model has emerged as a novel, structured, touch-based approach to evaluating neonates’ general conditions, with growing evidence supporting its validity and reliability in NICU settings. However, there is a critical need to integrate this method into clinical workflows and explore its translational potential in improving neonatal care. This paper aims to consolidate the body of evidence surrounding the NAME model and propose a clinically implementable strategy to enhance neonatal assessment, early detection of complications, and overall health outcomes in NICU settings … MORE

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Neonatal osteopathic care Integrating neonatal osteopathic care with global implementation protocols to improve health and economic outcomes

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14 March 2026

Neonatal osteopathic care Integrating neonatal osteopathic care with global implementation protocols to improve health and economic outcomes

This innovation represents the first systematic integration of evidence-based neonatal osteopathic care with global implementation protocols. It uniquely synthesizes findings from randomized controlled trials and a systematic review into a comprehensive, scalable framework. This framework can be adapted to diverse health care systems, ranging from high-resource neonatal intensive care units to basic facilities in lower-resource settings … MORE

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Osteopaths’ Perceptions and Practice Behaviours Regarding Preventive Health in Their Clinical Practice

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20 January 2026

Osteopaths’ Perceptions and Practice Behaviours Regarding Preventive Health in Their Clinical Practice

Australia’s National Preventive Health Strategy (NPHS) explicitly highlights the important role of primary care in screening for and supporting behaviour change to help reach preventive health goals. Given osteopaths’ position as primary care providers in Australia, their role in fulfilling the NPHS warrants consideration. In response, this study aims to investigate osteopaths’ perceptions regarding their role in preventive health and their practice behaviours regarding the key priority areas outlined in the NPHS … ABSTRACT

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Effect of osteopathic manipulative treatment on primary pelvic pain – A systematic review with meta-analysis

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10 November 2025

Effect of osteopathic manipulative treatment on primary pelvic pain – A systematic review with meta-analysis

The objective of this systematic review with meta-analysis is to evaluate the effectiveness of osteopathic manipulative treatment on primary pelvic pain … ABSTRACT

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Impact of touch interventions on brain activity in moderately preterm infants: study protocol for a pilot randomised controlled trial

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29 October 2025

Impact of touch interventions on brain activity in moderately preterm infants: study protocol for a pilot randomised controlled trial

Improving the quality of life for preterm children is a global health priority, given their vulnerability to neurocognitive impairments and adverse health consequences. Lack of posthospital care further exacerbates these risks, necessitating effective interventions during the neonatal period. This protocol for a pilot study aims to investigate the effects of touch interventions, including physiotherapy and osteopathic manipulative treatment, on brain activity in moderately preterm infants using brain functional MRI (fMRI), computerised EEG and metabolomics … MORE

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European research Priorities for Osteopathic Care (PROCare): a sequential exploratory investigation and survey

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19 October 2025

European research Priorities for Osteopathic Care (PROCare): a sequential exploratory investigation and survey

The aim of this study is to identify and analyse research priorities across the osteopathic profession internationally, to determine how different interested parties conceptualise research importance and to examine how contextual factors influence research prioritisation … MORE

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The changing face of acute low back pain management by physiotherapists, osteopaths and chiropractors in the UK: a 20-year comparison from 2003 to 2023

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2 October 2025

The changing face of acute low back pain management by physiotherapists, osteopaths and chiropractors in the UK: a 20-year comparison from 2003 to 2023

Low back pain (LBP) remains a leading source of disability and societal cost. In the UK, physiotherapists, osteopaths, and chiropractors are front-line providers of LBP care. Despite widespread dissemination of clinical guidelines, little is known about how their clinical practice has changed over time. National surveys of UK physiotherapists, osteopaths and chiropractors in 2003 and 2023 were conducted, using an identical acute non-specific LBP vignette to assess reported use of investigations and interventions at both time points … MORE

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