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Longitudinal outcomes among patients with fibromyalgia, chronic widespread pain, or localized chronic low back pain

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24 July 2025

Longitudinal outcomes among patients with fibromyalgia, chronic widespread pain, or localized chronic low back pain

The objective of this study was to compare longitudinal outcomes of patients with FM, CWP, or localized chronic low back pain (LBP) to determine whether FM is an extreme manifestation of the CWP continuum … MORE

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Carpal tunnel dimensions following osteopathic manipulation utilizing dorsal carpal arch muscle energy: a pilot study

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24 July 2025

Carpal tunnel dimensions following osteopathic manipulation utilizing dorsal carpal arch muscle energy: a pilot study

Carpal tunnel syndrome (CTS) is the most common entrapment neuropathy. When mild to moderate in severity, nonoperative treatments including osteopathic manipulative treatment (OMT) have been found to be effective. Studies have been carried out to quantify the mechanism of such treatments with cadaver studies, magnetic resonance imaging (MRI), and ultrasound. This pilot project investigated the mechanism of a previously undescribed technique of nonoperative carpal tunnel treatment, dorsal carpal arch muscle energy (DCA-ME), which focuses on the dorsal arch (trapezium, trapezoid, capitate, and hamate bones) manipulating the bones to redome the arch, round the tunnel, and increase its volume. Although the actual effectiveness of such manipulation in the treatment of CTS can only be assessed and quantified in patients with the disorder, this initial study was carried out to see if it was feasible for physical changes following DCA-ME to be quantified with ultrasound … MORE

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The role of osteopathic manipulative treatment in neurological disorders: A critical review with clinical advice

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7 July 2025

The role of osteopathic manipulative treatment in neurological disorders: A critical review with clinical advice

Since more people age and live longer with chronic disease, it is important to develop complementary and adjunctive approaches to improve body homeostasis and ensure the highest possible level of well-being for people affected by neurological disorders, besides the known benefits related to neurorehabilitation. In this context, osteopathic manipulative treatment (OMT) should be considered a promising holistic treatment to manage better pain and symptoms related to the chronic stages of neurological diseases. The primary purpose of this review is to examine the existing literature to determine the role and effects of OMT in patients affected by neurological disorders, giving some clinical advice … MORE
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Employment characteristics of individuals who received osteopathic care: a retrospective cross-sectional observational study

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4 June 2025

Employment characteristics of individuals who received osteopathic care: a retrospective cross-sectional observational study

The profile and clinical presentation of people consulting osteopaths in Belgium has been studied and reported before. Information on employment aspects of such individuals is lacking. The aim of this cross-sectional observational study was to contribute to filling this gap … ABSTRACT

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Investigating the trustworthiness of randomized controlled trials in osteopathic research: a systematic review with meta-analysis

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31 May 2025

Investigating the trustworthiness of randomized controlled trials in osteopathic research: a systematic review with meta-analysis

The objective of this review is to systematically investigate trustworthiness (methodological rigor, transparency, good governance, research integrity, and absence of misconduct) in randomized controlled trials (RCTs) of osteopathic manual therapy … MORE

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The effect of osteopathic manipulative treatment on chronic rhinosinusitis

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31 May 2025

The effect of osteopathic manipulative treatment on chronic rhinosinusitis

Chronic rhinosinusitis (CRS) is a prevalent inflammatory disease of the paranasal sinuses that may significantly impair quality of life. CRS may also benefit from the application of manual techniques through osteopathic manipulative treatment (OMT), which aims to improve venous and lymphatic circulation, sympathetic and parasympathetic outflow, and cervicothoracic somatic dysfunction. This study aimed to assess whether OMT focused on lymphatic drainage of cranial structures can provide immediate, as well as sustained, relief of CRS symptoms … MORE

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Effects of a single osteopathic manipulative treatment on intraocular pressure reduction: a pilot study

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28 May 2025

Effects of a single osteopathic manipulative treatment on intraocular pressure reduction: a pilot study

Research on the effects of osteopathic manipulative treatment (OMT) on visual functions and conditions is very limited. This study continues the exploration on the application of OMT with the intent of lowering intraocular pressure (IOP). A pilot randomized clinical trial was conducted to assess the impact of one OMT session on patients diagnosed with suspected ocular hypertension (OHT) or glaucoma … MORE

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Acute changes in functional connectivity associated with first osteopathic manual treatment in chronic low back pain spatially overlap with opioid receptor expression

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13 May 2025

Acute changes in functional connectivity associated with first osteopathic manual treatment in chronic low back pain spatially overlap with opioid receptor expression

Osteopathic Manipulative Treatment (OMT) has emerged as a therapeutic approach for chronic low back pain (cLBP). Previous Magnetic Resonance (MR) studies have demonstrated that four weeks of OMT alter resting-state functional connectivity (rs-FC) in the somatosensory cortex, prefrontal regions, and frontal operculum/insula. However, it remains unclear whether a single session of OMT can immediately affect brain rs-FC … MORE

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Alignment between the research question, design and terminology is required in manual therapy trials – a methodological study.

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12 May 2025

Alignment between the research question, design and terminology is required in manual therapy trials – a methodological study.

This methodological study aimed to assess the design, reporting, and risk of bias in effectiveness trials in manual therapy, comparing pragmatic with non-pragmatic trials and trials with and without placebo controls … ABSTRACT

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Placebo effects in osteopathy and other manual therapies – What they are and why they matter to clinical practice, education, and research

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9 May 2025

Placebo effects in osteopathy and other manual therapies – What they are and why they matter to clinical practice, education, and research

Placebo effects are measurable changes in health outcomes arising from treatment context, driven by learning and expectancy mechanisms. While increasingly well documented and understood, their role in osteopathic and other manual therapies remains underexplored. Given the inherently complex and interpersonal nature of these interventions, understanding placebo and nocebo effects is essential for refining clinical practice, education, and research.
This narrative review synthesises current research on placebo mechanisms and their implications for osteopathic practice, education, and research. A non-systematic literature search was conducted using Google Scholar, structured by pre-defined learning outcomes, and prioritising high-quality studies and systematic reviews where available. Contradictory findings were sought and critically appraised to provide a balanced perspective … MORE
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