19 April 2026
Patients With Chronic Low Back Pain Without Advanced Disk Degeneration Exhibit Gut Microbiome Dysbiosis: Evidence From an Age- , Sex- , and BMI- Matched Pilot Study
Chronic low back pain (LBP) is the leading cause of disability worldwide, yet its underlying pathophysiology remains poorly understood. Current diagnostic techniques rely heavily on imaging, which is insufficient for identifying inflammatory or systemic contributors. Emerging evidence suggests a role for gut microbiome dysbiosis in inflammatory pain pathways, yet its specific contribution to chronic LBP remains unclear. The aim of this study is to investigate gut microbiome alterations in chronic LBP patients compared to healthy controls … MORE
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