Klinische Effektivität einer osteopathi- schen Behandlung bei Migräne

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Authors: Cerritelli F, Ginevri L, Messi G, Caprari E, Di Vincenzo M, Renzetti C, Cozzolino V, Barlafante G, Foschi N, Provinciali L.
Journal: Osteopathische Medizin. 2016;17(1):9-16

Objective: To assess the e ectiveness of OMT on chronic migraineurs using HIT-6 questionnaire, drug consumption, days of migraine, pain intensity and functional disability.

Design: 3-armed randomized controlled trial setting: all patients admitted in the De- partment of Neurology of Ancona’s United Hospitals, Italy, with a diagnosis of migraine and without chronic illness were considered eligible for the study.

Interventions: Patients were randomly divi- ded into three groups: (1) OMT + medica- tion therapy, (2) sham + medication therapy and (3) medication therapy only. Patients received 8 treatments in a study period of 6 months. Main outcome measures: Chan- ging from baseline HIT-6 score.

Results: 105 subjects were included. At the end of the study, ANOVA showed that OMT signi cantly reduced HIT-6 score (mean change scores OMT – conventional care: −8.74; 95% con denceinterval [CI] −12.96 to −4.52, p<0.001; OMT – sham: −6.62; 95% CI −10.85 to −2.41; p<0.001), drug con- sumption (OMT – sham: RR=0.22, 95% CI 0.11–0.40; OMT – control: RR=0.20,95% CI 0.10–0.36), days of migraine (OMT – con- ventional care: M = −21.06; 95% CI −23.19 to −18.92; p<0.001 and OMT – sham: −17.43; 95% CI −19.57 to −15.29; p<0.001), pain intensity (OMT – sham: RR=0.42, 95% CI 0.24—0.69; OMT – control: RR=0.31, 95% CI 0.19–0.49) and functional disability (p<0.001).

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