Does case misclassification threaten the validity of studies investigating the relationship between neck manipulation and vertebral artery dissection stroke? Yes

Does case misclassification threaten the validity of studies investigating the relationship between neck manipulation and vertebral artery dissection stroke? Yes

For patients and health care providers who are considering spinal manipulative therapy of the neck, it is crucial to establish if it is a trigger for cervical artery dissection and/or stroke, and if it is, the magnitude of the risk. The authors of this article discuss the biological plausibility of how neck manipulation could cause cervical artery dissection and also discuss how case misclassification threatens the validity of influential published studies that have investigated the relationship between neck manipulation and dissection … MORE